HS-GC-IMS-Based metabonomics study of Baihe Jizihuang Tang in a rat model of chronic unpredictable mild stress.
The aim of this study was to investigate the differences in volatile organic compounds (VOCs) obtained from the feces of a Baihe Jizihuang Tang (BHT)-treated rat depression model. Rats were subjected to chronic unpredictable mild stress (CUMS), and the differences in VOCs were analyzed by headspace-gas chromatography-ion mobility spectrometry (HS-GC-IMS), NIST software, principal component analysis, and orthogonal partial least squares discriminant analysis.
Eleven biomarkers were identified on the basis of VOC migration time, and their relative peak intensities were analyzed. A metabonomic model was established using multivariate statistical analysis.
The study demonstrated the metabonomics of CUMS rats and the intervention effect of BHT and also highlighted the potential therapeutic effects of the traditional Chinese medicine (TCM) Jingfang for the clinical treatment of complex diseases, which was in line with the holistic and systemic approaches of TCM.
HPX siRNA |
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20-abx919837 | Abbexa |
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HPX siRNA |
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20-abx919838 | Abbexa |
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HPX siRNA |
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20-abx902527 | Abbexa |
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Hpx (Myc-DDK-tagged) - Mouse hemopexin (Hpx) |
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MR207345 | Origene Technologies GmbH | 10 µg | Ask for price |
HPX (Myc-DDK-tagged)-Human hemopexin (HPX) |
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RC222271 | Origene Technologies GmbH | 10 µg | Ask for price |
HPX Antibody |
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32919 | SAB | 100ul | EUR 439 |
HPX Antibody |
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32919-100ul | SAB | 100ul | EUR 302.4 |
HPX Antibody |
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E19-7415 | EnoGene | 100μg/100μl | EUR 225 |
Description: Available in various conjugation types. |
HPX Antibody |
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E561025-A-SE | EnoGene | 100ug | EUR 295 |
Description: Available in various conjugation types. |
HPX Antibody |
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E95603 | EnoGene | 100μg | EUR 255 |
Description: Available in various conjugation types. |
HPX Antibody |
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E305312 | EnoGene | 100ug/200ul | EUR 275 |
Description: Available in various conjugation types. |
Hpx Antibody |
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CAC08527-100ug | Biomatik Corporation | 100ug | EUR 314 |
Hpx Antibody |
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CAC08527-50ug | Biomatik Corporation | 50ug | EUR 199.2 |
HPX antibody |
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70R-33157 | Fitzgerald | 100 ug | EUR 451 |
Description: Rabbit polyclonal HPX antibody |
Hpx Antibody |
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1-CSB-PA010723LA01RA | Cusabio |
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Description: A polyclonal antibody against Hpx. Recognizes Hpx from Human, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB; Recommended dilution: WB:1:1000-1:5000 |
HPX Antibody |
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ABD7415 | Lifescience Market | 100 ug | EUR 525.6 |
HPX Antibody |
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1-CSB-PA14619A0Rb | Cusabio |
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Description: A polyclonal antibody against HPX. Recognizes HPX from Human. This antibody is Unconjugated. Tested in the following application: ELISA, IHC, IF; Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200 |
Hpx (untagged ORF) - Rat hemopexin (Hpx), (10 ug) |
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RN207569 | Origene Technologies GmbH | 10 µg | Ask for price |
HPX Rabbit pAb |
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E2505603 | EnoGene | 100ul | EUR 225 |
Description: Available in various conjugation types. |
HPX Rabbit pAb |
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A5603-100ul | Abclonal | 100 ul | EUR 369.6 |
HPX Rabbit pAb |
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A5603-200ul | Abclonal | 200 ul | EUR 550.8 |
HPX Rabbit pAb |
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A5603-20ul | Abclonal | 20 ul | EUR 219.6 |
HPX Rabbit pAb |
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A5603-50ul | Abclonal | 50 ul | EUR 267.6 |
Rat Hemopexin (Hpx) |
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1-CSB-YP010723RA | Cusabio |
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Description: Recombinant Rat Hemopexin(Hpx) expressed in Yeast |
Rat Hemopexin (Hpx) |
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1-CSB-EP010723RA | Cusabio |
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Description: Recombinant Rat Hemopexin(Hpx) expressed in E.coli |
HPX cloning plasmid |
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CSB-CL010723HU-10ug | Cusabio | 10ug | EUR 279.6 |
Description: A cloning plasmid for the HPX gene. |
HPX Blocking Peptide |
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DF7415-BP | Affbiotech | 1mg | EUR 234 |
Chicken Hemopexin(HPX) |
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QY-E80188 | Qayee Biotechnology | 96T | EUR 500 |
Hpx (Myc-DDK-tagged ORF) - Rat hemopexin (Hpx), (10 ug) |
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RR207569 | Origene Technologies GmbH | 10 µg | Ask for price |
Hemopexin (HPX) Antibody |
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20-abx110423 | Abbexa |
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Hemopexin (HPX) Antibody |
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20-abx100261 | Abbexa |
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Hemopexin (HPX) Antibody |
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20-abx100262 | Abbexa |
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Hemopexin (HPX) Antibody |
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20-abx100263 | Abbexa |
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Hemopexin (HPX) Antibody |
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20-abx130204 | Abbexa |
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Hemopexin (HPX) Antibody |
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20-abx141489 | Abbexa |
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Hemopexin (HPX) Antibody |
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abx037974-100ug | Abbexa | 100 ug | EUR 469.2 |
Hemopexin (HPX) Antibody |
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abx032918-400ul | Abbexa | 400 ul | EUR 627.6 |
Hemopexin (HPX) Antibody |
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abx032918-80l | Abbexa | 80 µl | EUR 343.2 |
Hemopexin (HPX) Antibody |
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abx018663-100ul | Abbexa | 100 ul | EUR 410.4 |
Hemopexin (HPX) Antibody |
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20-abx004282 | Abbexa |
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Hemopexin (HPX) Antibody |
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abx233829-100ug | Abbexa | 100 ug | EUR 661.2 |
Hemopexin (HPX) Antibody |
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20-abx172765 | Abbexa |
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Hemopexin (HPX) Antibody |
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20-abx172766 | Abbexa |
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Hemopexin (HPX) Antibody |
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20-abx172767 | Abbexa |
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Hemopexin (HPX) Antibody |
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20-abx176803 | Abbexa |
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Hemopexin (HPX) Antibody |
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20-abx176804 | Abbexa |
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Hemopexin (HPX) Antibody |
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20-abx302284 | Abbexa |
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Hemopexin Antibody / HPX |
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F54425-0.08ML | NSJ Bioreagents | 0.08 ml | EUR 140.25 |
Description: HPX is a plasma glycoprotein that binds heme with high affinity. The protein is an acute phase protein that transports heme from the plasma to the liver and may be involved in protecting cells from oxidative stress. |
Hemopexin Antibody / HPX |
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F54425-0.4ML | NSJ Bioreagents | 0.4 ml | EUR 322.15 |
Description: HPX is a plasma glycoprotein that binds heme with high affinity. The protein is an acute phase protein that transports heme from the plasma to the liver and may be involved in protecting cells from oxidative stress. |
Hemopexin Antibody / HPX |
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RQ7000 | NSJ Bioreagents | 100 ug | EUR 356.15 |
Description: Hemopexin (or haemopexin; Hpx; Hx), also known as beta-1B-glycoprotein, is a glycoprotein that in humans is encoded by the HPX gene and belongs to hemopexin family of proteins. This gene encodes a plasma glycoprotein that binds heme with high affinity. The encoded protein is an acute phase protein that transports heme from the plasma to the liver and may be involved in protecting cells from oxidative stress. |
Hemopexin Antibody / HPX |
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RQ5019 | NSJ Bioreagents | 100ul | EUR 356.15 |
Description: Hemopexin binds heme and transports it to the liver for breakdown and iron recovery, after which the free hemopexin returns to the circulation. [UniProt] |
Hemopexin (HPX) Antibody |
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abx004282-100l | Abbexa | 100 µl | EUR 400 |
Hemopexin (HPX) Antibody |
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abx004282-20l | Abbexa | 20 µl | EUR 175 |
Hemopexin (HPX) Antibody |
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abx004282-50l | Abbexa | 50 µl | EUR 275 |
Hemopexin (HPX) Antibody |
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abx100261-100l | Abbexa | 100 µl | EUR 237.5 |
Hemopexin (HPX) Antibody |
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abx100261-1ml | Abbexa | 1 ml | EUR 600 |
Hemopexin (HPX) Antibody |
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abx100261-200l | Abbexa | 200 µl | EUR 287.5 |
Hemopexin (HPX) Antibody |
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abx100262-100l | Abbexa | 100 µl | EUR 237.5 |
Hemopexin (HPX) Antibody |
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abx100262-1ml | Abbexa | 1 ml | EUR 600 |
Hemopexin (HPX) Antibody |
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abx100262-200l | Abbexa | 200 µl | EUR 287.5 |
Hemopexin (HPX) Antibody |
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abx100263-100l | Abbexa | 100 µl | EUR 275 |
Hemopexin (HPX) Antibody |
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abx100263-1ml | Abbexa | 1 ml | EUR 775 |
Hemopexin (HPX) Antibody |
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abx100263-200l | Abbexa | 200 µl | EUR 350 |
Hemopexin (HPX) Antibody |
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abx130204-100l | Abbexa | 100 µl | EUR 275 |
Hemopexin (HPX) Antibody |
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abx130204-1ml | Abbexa | 1 ml | EUR 775 |
Hemopexin (HPX) Antibody |
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abx130204-200l | Abbexa | 200 µl | EUR 350 |
Hemopexin (HPX) Antibody |
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abx172765-1ml | Abbexa | 1 ml | EUR 637.5 |
Hemopexin (HPX) Antibody |
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abx172767-1ml | Abbexa | 1 ml | EUR 812.5 |
Hemopexin (HPX) Antibody |
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abx110423-100l | Abbexa | 100 µl | EUR 162.5 |
Hemopexin (HPX) Antibody |
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abx302284-100g | Abbexa | 100 µg | EUR 362.5 |
Hemopexin (HPX) Antibody |
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abx302284-20g | Abbexa | 20 µg | EUR 162.5 |
Hemopexin (HPX) Antibody |
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abx302284-50g | Abbexa | 50 µg | EUR 250 |
Hemopexin (HPX) Antibody |
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abx037974-100g | Abbexa | 100 µg | EUR 337.5 |
Hemopexin (HPX) Antibody |
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abx032918-400l | Abbexa | 400 µl | EUR 518.75 |
Hemopexin (HPX) Antibody |
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abx018663-1mg | Abbexa | 1 mg | EUR 262.5 |
Hemopexin (HPX) Antibody |
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abx233829-100g | Abbexa | 100 µg | EUR 350 |
Hemopexin (HPX) Antibody |
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abx433628-100g | Abbexa | 100 µg | EUR 387.5 |
HPX Conjugated Antibody |
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C32919 | SAB | 100ul | EUR 476.4 |
Hpx Polyclonal Antibody |
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A52880 | EpiGentek |
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Recombinant Hemopexin (HPX) |
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RPB986Hu01 | Cloud-Clone | 10ug | EUR 140 |
Recombinant Hemopexin (HPX) |
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4-RPB986Hu01 | Cloud-Clone |
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Description: Recombinant Human Hemopexin expressed in: E.coli |
Recombinant Hemopexin (HPX) |
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RPB986Hu02 | Cloud-Clone | 10ug | EUR 140 |
Recombinant Hemopexin (HPX) |
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4-RPB986Hu02 | Cloud-Clone |
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Description: Recombinant Human Hemopexin expressed in: E.coli |
Recombinant Hemopexin (HPX) |
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RPB986Hu03 | Cloud-Clone | 10ug | EUR 142 |
Recombinant Hemopexin (HPX) |
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RPB986Ra01 | Cloud-Clone | 10ug | EUR 144 |
Recombinant Hemopexin (HPX) |
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4-RPB986Ra01 | Cloud-Clone |
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Description: Recombinant Rat Hemopexin expressed in: E.coli |
Recombinant Hemopexin (HPX) |
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RPB986Ra02 | Cloud-Clone | 10ug | EUR 144 |
Recombinant Hemopexin (HPX) |
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4-RPB986Ra02 | Cloud-Clone |
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Description: Recombinant Rat Hemopexin expressed in: E.coli |
Recombinant Hemopexin (HPX) |
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RPU41860-100ug | Biomatik Corporation | 100ug | EUR 431.2 |
Recombinant Hemopexin (HPX) |
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RPU41860-1mg | Biomatik Corporation | 1mg | EUR 1911 |
Recombinant Hemopexin (HPX) |
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RPU41860-50ug | Biomatik Corporation | 50ug | EUR 346.5 |
Recombinant Hemopexin (HPX) |
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RPU41861-100ug | Biomatik Corporation | 100ug | EUR 443.3 |
Recombinant Hemopexin (HPX) |
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RPU41861-1mg | Biomatik Corporation | 1mg | EUR 1965.6 |
Recombinant Hemopexin (HPX) |
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RPU41861-50ug | Biomatik Corporation | 50ug | EUR 356.4 |
Recombinant Hemopexin (HPX) |
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RPU41862-100ug | Biomatik Corporation | 100ug | EUR 431.2 |
Recombinant Hemopexin (HPX) |
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RPU41862-1mg | Biomatik Corporation | 1mg | EUR 1911 |
Recombinant Hemopexin (HPX) |
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RPU41862-50ug | Biomatik Corporation | 50ug | EUR 346.5 |
Recombinant Hemopexin (HPX) |
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RPU41863-100ug | Biomatik Corporation | 100ug | EUR 443.3 |
Recombinant Hemopexin (HPX) |
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RPU41863-1mg | Biomatik Corporation | 1mg | EUR 1965.6 |
Recombinant Hemopexin (HPX) |
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RPU41863-50ug | Biomatik Corporation | 50ug | EUR 356.4 |
Lenti ORF clone of Hpx (mGFP-tagged) - Mouse hemopexin (Hpx) |
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MR207345L4 | Origene Technologies GmbH | 10 µg | Ask for price |
Rat HPX ELISA Kit |
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ERH0117 | Abclonal | 96Tests | EUR 625.2 |
Goat HPX ELISA Kit |
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EGTH0117 | Abclonal | 96Tests | EUR 625.2 |
Lenti ORF clone of Hpx (Myc-DDK-tagged) - Mouse hemopexin (Hpx) |
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MR207345L3 | Origene Technologies GmbH | 10 µg | Ask for price |
HPX ELISA KIT|Human |
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EF006125 | Lifescience Market | 96 Tests | EUR 826.8 |
Human HPX ELISA Kit |
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EHH0117 | Abclonal | 96Tests | EUR 625.2 |
Human HPX ELISA Kit |
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ELA-E1986h | Lifescience Market | 96 Tests | EUR 988.8 |
HPX protein (His tag) |
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80R-3694 | Fitzgerald | 100 ug | EUR 337 |
Description: Purified recombinant HPX protein (His tag) |
Sheep HPX ELISA Kit |
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ESH0117 | Abclonal | 96Tests | EUR 625.2 |
Mouse HPX ELISA Kit |
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EMH0117 | Abclonal | 96Tests | EUR 625.2 |
Hpx sgRNA CRISPR Lentivector (Rat) (Target 2) |
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K6850703 | ABM | 1.0 ug DNA | EUR 184.8 |
Bovine HPX ELISA Kit |
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EBH0117 | Abclonal | 96Tests | EUR 625.2 |
Canine HPX ELISA Kit |
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ECH0117 | Abclonal | 96Tests | EUR 625.2 |
Monkey HPX ELISA Kit |
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EMKH0117 | Abclonal | 96Tests | EUR 625.2 |
Rabbit HPX ELISA Kit |
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ERTH0117 | Abclonal | 96Tests | EUR 625.2 |
HPX sgRNA CRISPR Lentivector (Human) (Target 2) |
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K0988303 | ABM | 1.0 ug DNA | EUR 184.8 |
Hpx sgRNA CRISPR Lentivector (Mouse) (Target 2) |
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K3830503 | ABM | 1.0 ug DNA | EUR 184.8 |
Chicken HPX ELISA Kit |
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ECKH0117 | Abclonal | 96Tests | EUR 625.2 |
Rat HPX shRNA Plasmid |
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20-abx985920 | Abbexa |
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Porcine HPX ELISA Kit |
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EPH0117 | Abclonal | 96Tests | EUR 625.2 |
This study augments the use of metabonomics based on HS-GC-IMS in research studies. Using this method, there is no need to pre-process samples by extraction or derivatization, and the VOC component of the sample can be detected directly and rapidly. In conclusion, this study establishes a simple, convenient, and fast technique, which can help identify clinical biomarkers for rapid medical diagnosis.